RESEARCH FUNDING
Howard Hughes Medical Institute Hanna Gray Fellowship
Leveraging epigenetics to improve peripheral nerve regeneration
2024-2032
Burroughs Wellcome Fund Postdoctoral Diversity Enrichment Program Fellowship - Revson Scholar
Defining the role of social touch somatosensory neurons in stress response: A novel skin-brain pathway for resilience
2024 - 2027
UNCF Ernest E. Just Postdoctoral Fellowship in the Life Sciences
2023 - 2027
K00 DSPAN NS125774 NINDS
Defining the Differential Role of Mrgprb4+ Social Touch Somatosensory Neurons in Pain Modulation and Frontolimbic Dysregulation During Chronic Inflammatory Pain
2023-2027
F99 DSPAN NS125774 NIMH - Impact score 11, no percentiles given
Characterizing effects of OFC astrocyte plasticity in inflammation response and stress vulnerability with single-cell resolution
2021-2023
F31 MH124425 NIMH - 6th percentile
Investigating chromatin-based mechanisms of astrocyte pathology during inflammation response and stress-induced behaviors
2020-2021
T32 MH087004
Mount Sinai Icahn School of Medicine Training Grant
2017-2019
PUBLICATIONS
First Author
Fulton, S. L., Bendl, J., Gameiro-Ros, I., Fullard, J. F., Al-Kachak, A., Lepack, A. E., ... & Maze, I. (2023). ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex. bioRxiv, 2023-05. (**In revision at Neuron)
Fulton SL*, Wenderski W*, Lepack AE*, Eagle, A.l., Fanutza,T., Bastle, R.M., Ramakrishnan, A., Hays, E.C., Neal, A., Bendl, J., Farrelly, L.A., Al-Kachak, A., Lyu, Y., Cetin, B., Chan, J.C., Tran, T.N., Neve, R.L., Roper, R.J., Brennand, K.J., Roussos, P., Schimenti, J.C., Friedman, A.K., Shen, L., Blitzer, R.D., Robison, A.J., Crabtree, G.J., & Maze, I. Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nature Communications, 13, 6384 (2022).
Fulton SL*, Wenderski W*, Lepack AE*, Eagle, A.l., Fanutza,T., Bastle, R.M., Ramakrishnan, A., Hays, E.C., Neal, A., Bendl, J., Farrelly, L.A., Al-Kachak, A., Lyu, Y., Cetin, B., Chan, J.C., Tran, T.N., Neve, R.L., Roper, R.J., Brennand, K.J., Roussos, P., Schimenti, J.C., Friedman, A.K., Shen, L., Blitzer, R.D., Robison, A.J., Crabtree, G.J., & Maze, I. Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nature Communications, 13, 6384 (2022).
Fulton, S. L*., Mitra, S.*, Lepack, A. E., Martin, J. A., Stewart, A. F., Converse, J., ... & Maze, I. (2022). Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats. Neuropsychopharmacology, 1-8
Fulton, S. L., Ryan Norris, Chang-Chi Hsieh, Eric Schoenfeld, Panayiotis Tsokas, , André Antonio Fenton, Todd Charlton Sacktor, , Jeremy D. Coplan (2021). "Lifelong reductions of PKMζ in ventral hippocampus of nonhuman primates exposed to early-life adversity due to unpredictable maternal care." Learning & Memory 28.9 (2021): 341-347
Co-Author
Stewart, A. F., Fulton, S. L., Durand-de Cuttoli, R., Thompson, R. E., Chen, P. J., Brindley, E., ... & Maze, I. Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation. bioRxiv. 2024 (**In Revision at Nature Neuroscience)
Zheng, Q., Bastle, R. M., Zhao, S., Kong, L., Vostal, L., Ramakrishnan, A., Fulton, S.L, ... & Maze, I. (2022). Histone monoaminylation dynamics are regulated by a single enzyme and promote neural rhythmicity. bioRxiv, 2022-12 (**In Press at Nature)
Burdge, J., Jhumka, A., Ogundare, S., Baer, N., Fulton, S.L.., Bistis, B., ... & Abdus-Saboor, I. (2024). Remote automated delivery of mechanical stimuli coupled to brain recordings in behaving mice. bioRxiv, 2024-05.
Al-Kachak, A., Di Salvo, G*, Fulton, S.L., Farrelly, L. A., Lepack, A. E., Bastle, R. M., Kong, L., ... & Maze, I. (2024). Histone serotonylation in dorsal raphe nucleus contributes to stress- and antidepressant-mediated gene expression and behavior. Nature Communications, 15, 5-42.
Pennington, Z.T., LaBanca, A.R., Sompolpong, P., Wick, Z.C., Feng, Y., Dong, Z., Francisco, T.R., Chen, L., Fulton, S.L., Maze, I. and Shuman, T, & Cai, D. J. (2024). Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior. Cell Reports.
Stewart, A. F., Lepack, A. L., Fulton, S. L., Safovich, P, & Maze, I. (2023). Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence. Molecular and Cellular Neuroscience, 103824
Ridout, K. K., Syed, S. A., Kao, H. T., Porton, B., Rozenboym, A. V., Tang, J., Fulton, S.L.,…& Coplan, J. (2022). Relationships between telomere length, plasma glucagon-like peptide 1, and insulin in early-life stress–exposed nonhuman primates. Biological Psychiatry Global Open Science, 2(1), 54-60.
Coplan, J. D., George, R., Syed, S. A., Rozenboym, A., Tang, J., Fulton, S. L., & Perera, T. D. (2021). Early Adversity and the Fate of Kynurenine Pathway Metabolites. Frontiers in human neuroscience, 15, 180.
Schoenfeld, E. M., Gupta, N. K., Syed, S. A., Rozenboym, A. V., Fulton, S. L., Jackowski, A. P., ... & Coplan, J. D Developmental Antecedents of Adult Macaque Neurogenesis: Early-Life Adversity, 5-HTTLPR Polymorphisms, and Adolescent Hippocampal Volume." Journal of Affective Disorders 286 (2021): 204-212
Lepack, A. E., Werner, C. T., Stewart, A. F., Fulton, S. L,...& Maze, I.M. (2020). Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science, 368(6487), 197-201.
Webler, R. D., Fulton, S., Perera, T. D., & Coplan, J. D. (2019). Maturational phase of hippocampal neurogenesis and cognitive flexibility. Neuroscience letters (PMID: 31430544)
Coplan, J. D., Rozenboym, A. V., Fulton, S. L., Panthangi, V., Tang, J., Thiramangalakdi, L., ... & Nemeroff, C. B. (2018). Reduced left ventricular dimension and function following early life stress: A thrifty phenotype hypothesis engendering risk for mood and anxiety disorders. Neurobiology of stress, 8, 202-210.
Coplan, J. D., Gupta, N. K., Flynn, S. K., Reiner, W. J., Gaita, D., Fulton, S. L., ... & Mann, J. J. (2018). Maternal Cerebrospinal Fluid Glutamate in Response to Variable Foraging Demand: Relationship to Cerebrospinal Fluid Serotonin Metabolites in Grown Offspring. Chronic Stress, 2, 2470547018785625.
Coplan, J. D., Syed, S., Perera, T. D., Fulton, S. L., Banerji, M. A., Dwork, A. J., & Kral, J. G. (2014). Glucagon-like peptide-1 as predictor of body mass index and dentate gyrus neurogenesis: neuroplasticity and the metabolic milieu. Neural plasticity, 2014.
Coplan, J. D., Fulton, S. L., Reiner, W., Jackowski, A., Panthangi, V., Perera, T. D., ... & Kaffman, A. (2014). Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders. Frontiers in behavioral neuroscience, 8.
Fulton, S., George, R., Perera, T., & Coplan, J. (2017). Stress-Induced Decrease in Atypical Protein Kinase M Zeta (PKMz)-Mediated LTP in the Non-Human Primate (NHP) Hippocampus is Regulated by Serotonergic Signaling: A Novel Mechanism for Behavioral Correlates of Affective Disorder. Biological Psychiatry, 81(10), S55-S56. (**Peer Reviewed Abstract)
Fulton, S. L. (2016). Protein Kinase M Zeta-Mediated LTP Maintenance in the Non-Human Primate Hippocampus: A role for Stress and Serotonergic Signaling in Affective Processing. CUNY Academic Works (**Master’s Thesis)
Fulton, S., Coplan, J. Perera, T. Mann, J. J. Early Life Stress (ELS) Compromises Adult Hippocampal Neurogenesis (AHN): Reduced Neuronal Maturation in a Non-Human Primate (NHP) Model of Stress-Induced Depression as a Potential Model of SSRI-Treatment. Biological Psychiatry (**Peer Reviewed Abstract) *Top Poster Award Biological Psychiatry Conference 2016
REVIEWS
Stewart, Andrew F., Fulton, S. L, and Maze, I.M. "Epigenetics of drug addiction." Cold Spring Harbor Perspectives in Medicine (2020): a040253.
Fulton, S. L., & Maze, I. (2019). Translational Molecular Approaches in Substance Abuse Research. In: Handbook of Experimental Pharmacology.